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A meta-analysis assessed the pooled effects of carnitine supplementation on glycemic markers across 41 randomized controlled trials that enrolled a total of 2,900 people (Zamani 2022)

CDDP-induced nephrotoxicity is associated with increased renal vascular resistance and morphological damage to the intracellular organelles, including cellular necrosis, loss of microvilli, changes in the number and size of lysosomes and mitochondrial vacuolization (14)