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It has been established that the speed of replication fork progression is regulated by TIPIN/TIMELESS complex with oligomer form of peroxiredoxin 2 (PRDX2), as a ROS sensor, in replisome
Axel Holst and Theodor Frlich, two Norwegian physicians studying shipboard beriberi contracted by ship's crews in the Norwegian Fishing Fleet, wanted a small test mammal to substitute for the pigeons then used in beriberi research
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