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doi: 10.1186/s12866-017-1027-1 97 KonstantiP.LigthartK.FryganasC.ConstantinosP.SmidtH.de VosW
They usually peak after a dose increase and ease within 12 weeks
Several molecules are currently available on the market, with partially different mechanisms of action, indications, dosages, and routes of administration (Table 1)
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The overlapping mechanisms would increase side effect risk without proportional benefit
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