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Researchers may examine how localized cellular activity interacts with broader signaling or structural pathways
Mol Genet Metab 71 : 315320 Werner H, Shen-Orr Z, Rauscher III FJ, Morris JF, Roberts Jr CT, LeRoith D (1995) Inhibition of cellular proliferation by the Wilms' tumor suppressor WT1 is associated with suppression of insulin-like growth factor I receptor gene expression
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More specifically, it is ambiguous whether this same pathway works in humans
