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Presented for research literature review only Gajewska J et al
Participants receiving the 8 mg and 12 mg doses reported significantly higher rates of GI side effects than those on lower doses
The regulation of OCs by the RANK/RANKL or JAK2/STAT3/RANKL axis stimulates their proliferation and differentiation, which affects their bone phagocytic function and causes bone loss [100,101,102]
Detailed strain information is provided in Table S1
Another issue involves dosing inconsistency
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