and JP23H04921 to Ya.S), AMED-CREST (grant number 24gm1410007h0004 to F.O.), the Takeda Science Foundation (to F.O.), the Naito Foundation (to F.O.), AMED-PRIME (grant number JP21gm6410012 to A.E.), the MEXT Leading Initiative for Excellent Young Researchers (to Yu.S.), Tottori University Research Support Project for the Next Generation (to Yu.S.), and the Grant for International Joint Research Project of the Institute of Medical Science, the University of Tokyo (to Ya.S
Unlike GLP-1 agonists, the changes are compositional rather than scale-weight driven: patients may not lose significant total body weight but will show meaningful reduction in waist circumference and visceral fat volume
It is envisioned that a specific AIE probe can be designed by decorating the TPE core with a particular functional group 26,57
GLP-1s are highly effective for most people, but they also have some serious risks
Among the three ethnic groups, the Indians have the highest IR state and the highest GLP-1 levels attesting to the adaptive compensatory nature of the GLP-1 secretion