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The Science 5-Amino-1MQ is a small molecule NNMT (nicotinamide N-methyltransferase) inhibitor that influences cellular energy metabolism by modulating the methylation of nicotinamidea key component in NAD+ synthesis and cellular energy production

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For histological analysis, the femoral and tibial condyles were fixed in 10% neutral buffered formalin, decalcified with 20% EDTA, embedded in paraffin, and sectioned into 5-m thick frontal slices