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We desperately need an effective way to treat knee pain. Certain factors that accelerate osteoarthritis, like age and genetic predisposition, are beyond our control, but others, like obesity and exercise, fall within it

Inhibition of vascular smooth muscle cell (VSMC) proliferation The proliferation and migration of normally quiescent VSMCs are central features of vascular diseases, including atherosclerosis and coronary restenosis (when treated arteries become blocked again) (47)

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