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1992;32(Suppl):S128-132
It may play a role in the heart's energy metabolism, but the actual benefits for healthy individuals are not clearly established
TB-500 binds G-actin (globular actin monomers), sequestering them and modulating actin polymerisation dynamics
No unexpected serious safety signals were reported in the topline data
KRAS mutant cancer cell lines (HCT116 and Panc-1) were more sensitive to GSTO1 inhibition (Supplementary Table 25)
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