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Each virtual patient was randomised to either a control group or one of four GLP-1 exposure groups semaglutide, tirzepatide, liraglutide or dulaglutide and given a standardised 100-unit BoNT-A dose
While some preclinical research has explored potential immunomodulatory effects of GLP-1 receptor agonists, there is currently insufficient clinical evidence to establish this as a mechanism for systemic symptoms in patients taking tirzepatide
10.1210/jc.2011-2407 15 LiA.SuX.HuS.WangY
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