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Users who switched from semaglutide to similar dual or triple agonists report better weight loss outcomes (15-25% versus 10-15%) and often lower nausea rates

Patients with diabetes require additional monitoring for retinopathy and hypoglycemia, especially if taking insulin or sulfonylureas

Counteracting Glucocorticoid Side Effects Evidence: Moderate (animal data) Long-term glucocorticoid use (prednisone, dexamethasone) causes well-documented problems: bone loss, muscle wasting, and impaired wound healing

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