B12 also plays a role in blood cell formation, DNA synthesis, nerve function, cognitive function, and promotes healthy skin and eyes
doi: 10.1681/ASN.2014111067 36 LiW.CuiM.WeiY.KongX.TangL.XuD
Recent research data has shown that the expression of lipid metabolism genes adiponectin (APN), Adipo R, AMPK, PPAR mRNA and protein is significantly increased after 48 hours of treatment with different concentrations of GLP-1 compared with the model group of adipose hepatocytes [108]
Intake of water-soluble dietary fiber, including pectins, gums, fructans and some resistant starches, has been shown to have many similar effects to the goals of GLP-1 therapy , such as: regulating both short and long-term glycemic control improving insulin sensitivity lowering blood cholesterol reducing the risk of cardiovascular disease 31,32 Both soluble and insoluble fibers also modulate microbiome composition and function, improving digestive health and supporting weight management
An epoxide hydrolase inhibitor reduces neuroinflammation in a mouse model of Alzheimers disease