More concerning, though rare, is the risk of acute pancreatitis, which has been reported with GLP-1 receptor agonists and is noted in the Warnings and Precautions sections of the prescribing information
PMID: 61 RanhotraHSharmaR
The pharmacist in me is cautiously optimistic about the safety profile
ELISA kits for brain-derived neurotrophic factor (BDNF), insulin-like growth factor-1 (IGF-1), glycogen synthase kinase-3 beta (GSK3), beta-site amyloid precursor protein cleaving enzyme 1 (Bace1), adenosine triphosphatase (ATPase), adenosine deaminase (ADA), acetylcholinesterase (AChE), and butyrylcholinesterase (BChE) were purchased from My BioSource (San Diego, CA, USA)
For example, when your body detects a foreign bacteria it mounts an immune response to increase body temperature that kills the bacteria and brings the body back to homeostasis - thats one side of the lever