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In the STEP trials, semaglutide 2.4mg weekly resulted in mean weight reductions of 1517% over 68 weeks, whilst tirzepatide in the SURPASS trials showed reductions of 1520% (Kushner et al

Protein and lipid pellets were discarded, while 10 L injections of supernatants were analyzed via a Vanquish UHPLC system (Thermo Fisher Scientific) coupled to a Q Exactive mass spectrometer (Thermo Fisher Scientific) utilizing an untargeted acquisition as previously reported 18

Your healthcare provider will help you understand realistic expectations based on your individual circumstances

(4) The bottom line here