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10.1016/j.cmet.2010.04.007 28 de VosW
This impending patent cliff is a material headwind for Novo Nordisk, but price reductions will drive a substantial uplift in the volume of patients on injectable semaglutide, through preferential reimbursement (by state or PMI payors) and improved affordability for the self-pay segment
(13) A key mechanism through which GLP-1 receptor agonists may influence bone metabolism is the osteoprotegerin (OPG)/RANKL/RANK pathway, which regulates osteoclast differentiation and bone resorption
This remains specific to TRIUMPH-1
It is a vasodilator, meaning that it can help open up the blood vessels
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