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doi: 10.1038/s41598-017-06484-6 225 QuanC.LiC.MaH.LiY.ZhangH
However, due to further research, doctors have found its anti-melanogenic characteristics and thus proposed it as a skin-lightening modality
PubMed Pickart L, Freedman JH, Loker WJ, et al
The dose-dependent effects of metformin on mitochondrial function underscore the importance of careful dosage management in clinical settings ( Furthermore, it is important to note that the effectiveness of metformin varies depending on the specific tissue and the dosage used ( 4 Unraveling the mechanisms behind metformin's antioxidant properties Metformin can modulate oxidative stress by inhibiting ROS production through pleiotropic actions, including AMPK modulation, mitochondrial complex I inhibition, and increased antioxidant enzyme activity
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