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Most of our patients describe it as less uncomfortable than a mosquito bite
This means that high serum B12 levels can persist for some time after large supplemental doses
Add in the potential for GI side effects that deplete fluids, and dehydration becomes a real risk during retatrutide protocols
Traditional medicine can help diagnose the issue
While that's substantially higher than the 600mg starting dose we generally favor for people new to NAC, it reflects the GlyNAC protocols studied in healthy-aging research.34 57 58 Some readers may prefer to start with a smaller serving for tolerability, but the clinical research on GlyNAC has generally evaluated gram-level doses of both ingredients, so it's unclear whether substantially lower amounts would provide the same benefits
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