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Here are the general instructions for proper use: Inject Semalix once weekly on the same day each week, unless your doctor advises otherwise
It represents a different mechanistic approach than retatrutide, combining amylin and GLP-1 agonism rather than GLP-1, GIP, and glucagon agonism
Contact your healthcare provider within 24-48 hours if dizziness persists for more than a few days, worsens after dose increases, or interferes with daily activities
If you choose to drink, do so minimally and not within 48 hours of your injection
Recent studies have found that increased level of GLP-1 in the hippocampus restores GABA and reverses this neurotoxic effect by reducing oxidative stress through the SIRT1/Nrf2/HO-1 pathway, promoting autophagy through the AMPK/mTOR pathway, and alleviating hippocampal apoptosis by inactivating pro-apoptotic kinase GSK-3 (Arab et al., 2023)
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