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Targeted disruption of peptide transporter Pept1 gene in mice significantly reduces dipeptide absorption in intestine

GLP-1 is also synthesized in neurons expressing preproglucagon in the nucleus tractus solitarius of the brainstem

[7] The protein encoded by this gene protects from CD95-induced apoptosis in cultured breast cancer cells and inhibits 5-lipoxygenase in blood cells, and its overexpression delays endothelial cell death and increases resistance to toxic challenges, especially oxidative stress

Dose adjustments are made based on symptoms and sensitivity under a clinicians guidance

This article does not prescribe doses