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Jonathan Kaplan, and Chief Nursing Officer at DrWell, noticed patients who switched from semaglutide to tirzepatide had better appetite suppression but an increase in food noise whereas patients on semaglutide had greater food noise reduction but less appetite suppression

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It is one potentially modifiable biochemical burden that may coexist with methylation imbalance, oxidative stress, copper-zinc dysregulation, pyroluria, gut dysfunction or immune activation