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Not dramatically, but enough that I could tell I was losing more than just fat
The design relies on the GLP-1 and GIP components generating enough insulin activity to counterbalance glucagon's glucose-raising tendency
For example, around 74% of patients who received the highest tirzepatide dose of 15 milligrams became free of MASH with no worsening of liver scarring after a year, compared with around 13% of those who received a placebo
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