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In adults with overweight or obesity (without diabetes) the semaglutide 2.4 mg dose produced an average weight reduction of about 15% of baseline body weight over ~68 weeks in the STEP 1 trial, a result that surprised many clinicians because it brought pharmacologic outcomes into a range previously associated with surgical interventions
Additional symptoms may include: Severe fatigue or lethargy Headache Rapid heart rate (tachycardia) potentially due to hypoglycaemia or dehydration Dehydration from persistent vomiting and diarrhoea (thirst, reduced urination, dizziness) The onset of symptoms following an overdose may not be immediate
Results can vary from person to person
Ozempic at 1 mg or greater dose has the FDA indication for this use
The National Health Service of the UK also suggests such simple things as getting lots of fresh air or trying to distract yourself with television or music
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