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These inflammation-associated hyperpigmented patches are of no clinical significance, their biological significance is unknown, and treatment is not required
For instance, when peripheral tissues become inflamed, the related signals might be transmitted to the brain through these receptors on the neurons, and the brain could then respond to these signals via neural pathways, thus regulating the level of peripheral inflammation
Senescence in Health and Disease
One primary challenge when dealing with compromised skin barriers is the decreased ability of the skin to function as a protective barrier, which is seen in patients with dermatological diseases such as psoriasis, eczema, or burns [345]
This game changer is projected to grow significantly, potentially exceeding $126 billion by 2030
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