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Future research should prioritize conducting long-term cost-effectiveness analyses incorporating all relevant comparators and adopting a societal perspective to comprehensively capture both direct and indirect costs and the long-term benefits of sustained weight loss
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Bupropion carries an FDA black box warning regarding suicidal thoughts in certain populations and is contraindicated for people with seizure disorders or eating disorders
The compounded tirzepatide landscape has changed dramatically
A large retrospective study of over 18,000 patients found that those taking tirzepatide lost approximately 15.3% of body weight in one year compared to 8.3% with semaglutide
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