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The new label for Ozempic is based on the results of the FLOW trial, which showed a statistically significant reduction in kidney disease progression, as well as cardiovascular and kidney death with a 1 mg/kg weekly dose of the injectable drug compared to placebo

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Sergey Terushkin, MD, FACS Last Updated: April 30, 2026 If your weight loss has slowed or stopped on semaglutide, youre not aloneplateaus are a normal biological response

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These conditions are closely linked and substantially increase the risk of cardiovascular disease, stroke, chronic kidney disease, neuropathy, retinopathy, and premature mortality

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Increasing evidence has demonstrated that GLP-1 analogues can cross the blood-brain barrier, protect dopaminergic neurons in the substantia nigra, and rescue motor activity and cognitive functions in PD animal models (5961)

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