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RNA Extraction and Quantitative Reverse Transcription-Polymerase Chain Reaction (qRT-PCR) Total RNA was extracted from cellular and cerebral samples using TRIzol reagent (Invitrogen, Carlsbad, CA, United States)
It presents in two forms
Studies evaluating GHK-Cus wound healing activity reported a 67% reduction in wound healing time compared to controls in preclinical models (Pickart, 1973)
Supplementary Table 5 (download XLSX Investigated_Drug_MoA (Names of all MoA classes with more than five drugs, area under the curve values from ROC curve analysis, number of drugs in the MoA Class, drug names) / t-test_p-values ( P values per metabolite and MoA class from t -test comparing drugs of an MoA class to all other drugs) / mean_zscores_metabolites (mean z-score per metabolite across all drug perturbations of an MoA class) / PEA_p-values ( P values per metabolic pathway (KEGG) and MoA class from pathway enrichment analysis (PEA) using all drugs from an MoA) / PEA_q-values ( q values per metabolic pathway (KEGG) and MoA class from PEA using all drugs from an MoA) / mean_ zscores_pathways (mean z-score per metabolite pathway across all drug perturbations of an MoA class) / median_zscores_pathways (median z-score per metabolite pathway across all drug perturbations of an MoA class)
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