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Months 3-6: Approaching the Maintenance Phase What the trials documented: By around month four (week 17), the REDEFINE protocol reached the 2.4 mg maintenance dose, and weight loss continued to accrue beyond that point through the 68-week primary endpoint (Aronne et al., 2025)
It functions as an electron carrier in cellular respiration and as a substrate for sirtuins (longevity proteins) and PARP enzymes (DNA repair proteins)
The link between B12 and fat burning lies in its role in converting food into usable energy
Br J Haematol (2004) 124(6):697711
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