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Rizzo JF 3rd et al

Other significantly downregulated proteins not related to CVD included secreted frizzled-related protein-4 (sFRP4) and liver fatty acid binding protein (LFABP), whereas granulin (GRN) was significantly upregulated

But these drugs do expire after a few weeks, and microdosing could increase the risk of inadvertently using them after their expiration date

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In addition, all patients treated with tesamorelin should be monitored periodically for changes in glucose metabolism to diagnose those who develop impaired glucose tolerance or diabetes