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Elevated insulin inhibits hormone-sensitive lipase, the enzyme responsible for breaking down stored triglycerides

Four decades of in vitro experiments have characterized the most important molecular pathways of LTP/LTD and found a rich set of stimulation protocols to explore the variables controlling plasticity induction (for a review see Malenka and Bear 11 )

Standard readouts include histological scoring of tissue sections, immunohistochemical staining for repair-associated markers, and quantitative PCR for growth factor gene expression

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A randomized, double-blind, placebo-controlled study of oral AOD9604 in overweight adults