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Glucagon-like peptide (GLP)-1: the incretin effect and gut-renal axis GLP-1 was discovered to be one of the key hormones to underlie the so-called incretin effect, i.e

Of the study cohort, 92% had type 2 diabetes and 86% had obesity

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Unlike oral supplements, which must pass through the digestive system and may be poorly absorbed, B12 injections bypass the gut entirely

The results showed that over 72 weeks, patients on the 10 mg dose lost an average of about 12.8% of their body weight, and those on the 15 mg dose lost an average of 14.7% of their body weight