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100 , E871875 (2015)
In high-fructose-induced nephropathy, carbohydrate-responsive element-binding protein--mediated transcriptional activation of TXNIP leads to lipid peroxidation and drives ferroptosis in renal tubular epithelial cells, thereby exacerbating renal injury (96)
Sestrin 2 is a leucine sensor that inhibits mTORC1 signaling [87], providing an interesting link between amino acid sensing, mTOR, and NRF2-KEAP1 pathway
Alternative clinical pathway
Liu H, Ma X, Liu S, Du B, Cheng N, Wang Y, Zhang Y (2020) The Nicotiana tabacum L
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