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Goldstein said there are two likely reasons
As with any medication, side effects are possible
Among the 21 evaluable patients, 5 patients achieved partial response (PR), and 7 patients experienced stable disease (SD)
before meals, use of the liquid formulation to improve absorption and facilitate dose titration to a maximum dose of 40 mg/day and use of drug holidays or dose reductions (e.g., 5 mg, before two main meals of the day) whenever clinically possible
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doi: 10.1111/j.1476-5381.2011.01480.x 16 ChaiY
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