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Tumors have evolved a unique microenvironment, and typically display a more acidic condition, hypoxia, overexpressed reactive oxygen species (ROS), and glutathione (GSH) owing to their rapid proliferation and metabolism (Zhou et al., 2018
En particular, la glutatin reductasa pareciera ser una buena diana teraputica para la accin de antimalricos, ya que la glutatin reductasa del parsito Plasmodium falciparum es significativamente diferente en cuanto a estructura y plegamiento a la glutatin reductasa de los mamferos
Growth hormone (GH)-releasing peptide-6 requires endogenous hypothalamic GH-releasing hormone for maximal GH stimulation1
Neurochem Res 40:139150
Shi, M.M
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