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The extended titration schedule helps minimize gastrointestinal adverse effects such as nausea, vomiting, and diarrhea, which are the most common reasons for treatment discontinuation
Biochem J 2001
For example, California, citing budget constraints, put Wegovy on a waiting list and limited it only to patients with certain co-conditions while studying overall impact
Forest plot of Albiglutide versus comparators on the risk of overall Respiratory diseases
Disproportionality signals for IGE All five GLP-1RAs had statistically significant reporting odds ratios (RORs) for IGE: Semaglutide: ROR 24.8 Dulaglutide: ROR 14.7 Liraglutide: ROR 13.7 Exenatide: ROR 5.4 Tirzepatide: ROR 18.3 This analysis confirms that these drugs are significantly more likely to be reported in conjunction with IGE compared to other medications
