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More severe side-effects of tirzepatide and semaglutide may include: Vision changes Pancreatitis Kidney failure Gallbladder issues Allergic reactions
The GLP-1 family acts heavily on the gut-brain axis through slowed digestion and reduced hunger signalling
Body mass index improvement reduces total knee arthroplasty complications among patients who have extreme, but not severe, obesity
It may never have been there to begin with
Wegovy : Contains semaglutide and is FDA-approved for long-term weight reduction in qualifying patients
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![Mechanism of action of GLP-1 [25]](https://www.researchgate.net/profile/Asfandyar-Sheikh/publication/256289222/figure/fig1/AS:614177232142337@1523442671231/Mechanism-of-action-of-GLP-1-25.png)
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