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Patients should maintain regular dental check-ups while taking tirzepatide, as changes in eating patterns, potential dry mouth, and altered oral hygiene habits related to nausea may affect dental health
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In ATTAIN-1, adverse event-related discontinuation rates were 5.3% with orforglipron 6 mg, 7.6% with 12 mg, and 10.3% with 36 mg, compared with 2.7% with placebo
It can also increase nausea and dehydration when combined with Wegovy
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