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PMID: 24828499

In plants for example, whole tissue NADPH:NADP + ratios are typically reported to be in the range of 1:1 to 2:1, which is of a similar magnitude as that reported by NAPstar sensors for the cytosol NADPH:NADP + ratio, please also see our recent review for a summary of the situation in plants 36

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By bypassing the digestive system, this therapy allows for higher therapeutic doses without gastrointestinal side effects, helping patients feel revitalized, supported, and rebalanced more quickly than oral supplementation alone