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Freezing and thawing a reconstituted peptide can cause the formation of ice crystals that, on a microscopic level, can shear and degrade the peptide chains
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doi:10.1126/scitranslmed.aan0972 13
Why Weight Loss Medicines Can Trigger Hair Shedding Rapid weight loss can cause telogen effluvium diffuse hair shedding triggered by caloric restriction, nutritional deficiencies, and metabolic stress which typically begins two to four months after the triggering event and is usually self-limiting
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