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The visceral adipose tissue of insulin-resistant vs insulin-sensitive obese patients shows marked differences in the DNA methylation landscape, with the most relevant changes observed at the promoter of genes involved in adiposity, diabetes development, chronic inflammation and aging such as COL9A1, CD44, IGF2BP1, ADAM2, TET1, ZNF714, ADCY9, TBX5, and HDACM [127]
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DR can be classified as background DR, severe nonproliferative DR, and proliferative DR based on its severity
10.1016/S0960-9822(03)00250-1 267 YadavV
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