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In addition, weight loss, body fat loss and improved glucose tolerance was also reported in clinical trials in obese men, as well as cardiovascular benefits ( 2.3 Insulin resistance Insulin regulates cell growth, gene expression, protein synthesis, mitochondrial function, and autophagy

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Johnstone AM, Murison SD, Duncan JS, Rance KA, Speakman JR: Factors influencing variation in basal metabolic rate include fat-free mass, fat mass, age, and circulating thyroxine but not sex, circulating leptin, or triiodothyronine