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Peptides have been used to treat medical conditions for more than a century
This inhibition mode in hTYR is noteworthy, as it suggests that the search for and optimization of efficient and safe peptide-based inhibitors may become a key direction in the development of human tyrosinase inhibitors
The same LASSS treatment also conferred nitration resistance with a greater effect for Y198 than Y250, indicating a novel mechanism independent of an anti-oxidative function of LASSS
Gawryluk JW, Wang JF, Andreazza AC, Shao L, Young LT
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