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Data were acquired using an MS3-based TMT method using the following scan parameters: scan sequence began with an MS1 master scan (Orbitrap analysis, resolution 120,000, 4001700 m/z, RF lens 60%, automatic gain control [AGC] target 2E5, maximum injection time 50 ms, centroid mode) with dynamic exclusion enabled (repeat count 1, duration 15 s)

While early onset may indicate physiological adaptation to receptor activation, detection bias from intensified early monitoring cannot be excluded

EXPECTED EFFECTS 1-2 Weeks: Users typically experience improved sleep quality as melatonin levels normalize, accompanied by increased feelings of well-being and reduced stress

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Ipamorelin acts as a pulse-triggering secretagogue through GHSR-1a