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213 Instead, inhibition of the H 2 S-synthesising trans-sulphuration pathway enzymes CBS and CSE, together with 3-MST, still holds great promise for cancer treatment, 81,143,214 as outlined below

Therefore, cysteine may be a conditionally essential amino acid in individuals with SCD for the synthesis of GSH

Dopamine supplementation would be evident, but this hydrophilic neurotransmitter does not cross the BBB and cannot enter the CNS due to brain endothelial tight junctions, active brain endothelial metabolism and lack of transporters [5]

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