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For some patients, gastrointestinal side effects, including heartburn, may diminish over time as the body adjusts to the medication
The relative risk ratio (95% confidence interval) of reaching CKD stage 5, after adjusting for the above traditional risk factors was 1.64 (1.22-2.21, p 300mg/24h), and 225 adults with severe albuminuria of whom 99 progressed to end-stage kidney disease (ESKD)
J Clin Invest 1983
23 :S14
J.JelinekL.et al (2009)
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