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Exenatide treatment did not changed significantly LVEF, myocardial perfusion or oxidative metabolism in T2DM patients with LV systolic dysfunction, having an overall similar effect of glargine insulin [152]
However, CagriSema and retatrutide (both in late-stage development) more closely match tirzepatide weight loss results , with CagriSema achieving 20% and retatrutide achieving up to 29% body weight reduction in trials
Zhu X, Sakamoto S, Ishii C, Smith MD, Ito K, Obayashi M, et al
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