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Standard Dosing Parameters Primary Application Dosing 1-2 mg daily 2-3 mg daily or 2 mg 2-3x per week 1-2 mg daily (injectable or topical) 2-5 mg daily under medical supervision Clinical studies used 0.3 mg/mL injections, while systemic wound healing in animal studies used approximately 1.1 mg/kg body weight (translating to ~75 mg total for humans in divided doses)
In short, an injection will provide a higher dose of B12 at regular intervals, whilst oral supplements have a lower dosage and can be taken every day
Yet, it is not known whether choline deficiency can increase the susceptibility to cancer in humans (2)
Liu J, Bai R, Chai Z, Cooper ME, Zimmet PZ, Zhang L
In humans, this disorder is called "Ataxia with Vitamin E Deficiency" (AVED
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