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Leg cramps are not listed as a recognised adverse effect in UK Summaries of Product Characteristics for GLP-1 receptor agonists

The clinical name for swallowing air while you eat is aerophagia, which involves swallowing so much air that it collects in your gut, leading to unpleasant symptoms like excessive burping, bloating, flatulence, and stomach pain

The underlying pharmacology is more subtle: the affinity ratio of the three receptors has been calibrated by Eli Lilly to maximize the metabolic effect without compromising glycemic control

But the flip side is equally important

10.1016/j.biopen.2017.02.004 111 SenguptaV.SenguptaS.LazoA.WoodsP.NolanA.BremerN