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In this study, all GLP-1 RA treatments resulted in a significant reduction in average BG over the course of the study, whereas untreated PBS controls experienced no significant change in average BG ( Figure 5AB )
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10.1124/jpet.300.3.958 119
Through activation of these receptors, it enables investigation of integrated endocrine signaling pathways that regulate cellular energy sensing, metabolic enzyme activity, and nutrient responsive signaling in laboratory models[5]
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