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The most common are nausea, facial flushing, darkening of moles, headaches, and increased libido

Patients are most likely to experience them when they first start the medication or when other factors, such as dehydration or increased physical activity, come into play

Not all participants started at 0.5 mg, and escalation schedules varied by protocol arm

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Key Takeaways Stopping GLP-1 medications can make maintenance harder because hunger increases, fullness signals decrease, and calorie needs drop at a lower weight