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The animals were monitored daily from onset of disease and scored according to the following scheme: 0 = no clinical score, 1 = reduced tail tonus, 2 = hind leg paraparesis or hemiparesis, 3 = hind leg paralysis or hemiparalysis, 4 = tetraplegia or moribund, 5 = death
Relationship between frequency of SHMT-C1420T and latitude The T allele frequency of the cSHMT-C1420T polymorphism across Eurasia is shown in Figure 2
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Another member of this drug family, saroglitazar, a PPAR/ agonist, has shown promise in diabetic patients with dyslipidemia, while it has also been utilized in experimental models and clinical trials for the treatment of NASH in India, 31,32 exhibiting promising results
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